Sequence Variations in PCSK9, Low LDL, and Protection against Coronary Heart Disease. Cohen, Ph.D., Eric Boerwinkle, Ph.D., Thomas H. E-S theory was developed by psychologist Simon Baron-Cohen as a major reconceptualization of cognitive sex differences in the general population and in an. According to our research of New Jersey and other state lists there were 111 registered sex offenders living in Elizabeth, New Jersey as of April 05, 2017. You can use this page to view a list of all current 2017 Expo West exhibitors and narrow down that list using a variety of search terms. Inorganic lead (EHC 1. INTERNATIONAL PROGRAMME ON CHEMICAL SAFETY.
ENVIRONMENTAL HEALTH CRITERIA 1. INORGANIC LEAD. This report contains the collective views of an international group of. United Nations Environment Programme, the International. Labour Organisation, or the World Health Organization. The main. objective of the IPCS is to carry out and disseminate evaluations of. 2322 Cohen Diet PlansSupporting activities include the development of. Other activities. IPCS include the development of know- how for coping. The designations. Secretariat of the World Health Organization concerning the legal. The. mention of specific companies or of certain manufacturers' products. World. Health Organization in preference to others of a similar nature that. Errors and omissions excepted, the names of. Identity, physical and chemical properties, and analytical. Sources of human exposure. Environmental transport, distribution and transformation. Environmental levels and human exposure. Kinetics and metabolism in laboratory animals and humans. Effects on laboratory animals and in vitro systems. Evaluation of human health risks. IDENTITY, PHYSICAL AND CHEMICAL PROPERTIES, AND ANALYTICAL. METHODS. 2. 1. Physical and chemical properties of lead and its compounds. Analytical procedures. Ubikinoni (Koentsyymi Q10) 1.8.2016 (Päivitetty: 19.2.2017) Täydentävää lääketiedettä; Kuvassa mitokondrio. Ubikinoni tuottaa energiaa solujen. Sampling procedures. Sampling of environmental media. Sampling of biological materials. Analytical methods for lead. Analysis of lead in environmental. Analysis of lead in biological materials. Analytical procedures for biomarkers of. 2322 Cohen Diet ReviewsSOURCES OF HUMAN AND ENVIRONMENTAL EXPOSURE3. Natural occurrence. Environmental contamination from natural sources. Anthropogenic sources. Smelting and refining. Environmental pollution from production of lead. Consumption and uses of lead and its compounds. Sources of environmental exposure. ENVIRONMENTAL TRANSPORT, DISTRIBUTION AND TRANSFORMATION4. Transport and distribution between media. Atmospheric deposition. Transport to water and soil. Transport to biota. Aquatic organisms. Terrestrial organisms. Environmental transformation. Abiotic transformation. ENVIRONMENTAL LEVELS AND HUMAN EXPOSURE5. Inhalation route of exposure. Ambient air. 5. 1. Emissions from motor vehicles. Stationary sources. Air in the working environment. Smoking of tobacco. Exposure by ingestion. Food and alcoholic beverages. Food. 5. 2. 2. 2 Total intake from food. Alcoholic beverages. Dust and surface soils. Dust. 5. 2. 3. 2 Soil. Migration of lead from food containers. Miscellaneous exposure. Cosmetics and medicines. General population exposure. Blood lead concentrations of various populations. Adult populations. Remote populations. Occupational exposure. KINETICS AND METABOLISM IN LABORATORY ANIMALS AND HUMANS6. Absorption after inhalation. Animal studies. 6. Human studies. 6. Absorption of lead from the gastrointestinal tract. Animal studies. 6. Human studies. 6. Nutritional status and lead absorption. Dermal absorption. Human dermal absorption. The relationship of external lead exposure to blood. Ambient air. 6. 1. Food. 6. 1. 4. 3 Drinking- water. Soil and dust. 6. Total lead intake. Transplacental transfer. Elimination and excretion. Biological indices of lead exposure and body burden. EFFECTS ON LABORATORY ANIMALS AND IN VITRO TEST SYSTEMS7. Biochemical effects. Haem synthesis and haematopoiesis. Nervous system effects. Higher order behavioural toxicity. Mechanisms of lead- induced behavioural toxicity. Conclusions. 7. 2. Sensory organ toxicity. Cardiovascular system. Reproductive system. Immunological effects. Biochemical effects of lead. Haem synthesis. 8. Protoporphyrin levels. Coproporphyrin levels. Aminolaevulinic acid levels in. Aminolaevulinic acid dehydratase levels. Aminolaevulinic acid synthase. Other effects of decreased haem. Dihydrobiopterin reductase. Nicotinamide adenine dinucleotide synthetase. Nutritionally affected groups. Haematopoietic system. Pyrimidine- 5'- nucleotidase activity. Erythropoietin production. Historical perspective. Neurotoxic effects in adults. Central nervous system. Peripheral nervous system. Autonomic nervous system. Neurotoxic effects in children. Historical perspective. Population- based cross- sectional studies on. Tooth lead studies. Blood lead studies. Follow- up studies. Conclusions and limitations of. Prospective epidemiological studies on children. Common elements. 8. Study descriptions. Summary of differences between studies. Results of studies. Questions prospective studies have not. Attempting a consensus. Task group overview and interpretation of. Rationale. 8. 3. 6. The prospective studies. A quantitative assessment of the. Task group overview of cross- sectional. An interpretation of the overview of. Hearing impairment in children. Clinical studies. Epidemiological studies. Occupational cohorts. General population. Cohort mortality studies. Cardiovascular system. Blood pressure. 8. Studies on occupationally exposed. Studies in the general population. Other cardiovascular effects. Occupational studies. Studies in the general population. Gastrointestinal effects. Occupational exposure. Exposure of children. Occupational exposure. Exposure of children. Female populations. Male populations. Hormonal responses. Postnatal growth and stature. Effects on chromosomes. Carcinogenicity. 8. Occupational exposure and renal cancer. Effects on thyroid function. Occupational groups. Effects in children. Occupational exposure. Biomarkers for lead effects. EVALUATION OF HUMAN HEALTH RISKS9. Exposure assessment. General population exposure. Occupational exposures. Critical issues related to exposure evaluation. Sampling and analytical concerns. Relationship between exposure and dose. Surrogate measures of dose. Biochemical effects of lead. Haem synthesis. 9. Urinary coproporphyrin. Urinary aminolaevulinic acid in children. Urinary aminolaevulinic acid in adults. Aminolaevulinic acid dehydratase. Vitamin D metabolism. Dihydrobiopterin reductase. Haemopoietic system. Anaemia in adults. Anaemia in children. Erythrocyte pyrimidine- 5'- nucleotidase. Adults. 9. 6. 1. 1 Central nervous system. Peripheral nervous system. Autonomic nervous system. Children. 9. 6. 2. Type of effect. 9. Magnitude. 9. 6. 2. Reversibility/persistence. Age- specific sensitivity. Interactions/subgroups. RECOMMENDATIONS FOR PROTECTION OF HUMAN HEALTH1. Public health measures. Public health programmes. Screening, monitoring and assessment procedures. PREVIOUS EVALUATIONS BY INTERNATIONAL BODIES. NOTE TO READERS OF THE CRITERIA MONOGRAPHS. Every effort has been made to present information in the criteria. In the interest of all users of the Environmental Health. Criteria monographs, readers are requested to communicate any errors. Director of the International Programme. Chemical Safety, World Health Organization, Geneva, Switzerland, in. In addition, many EHC monographs have been devoted to. Other publications have been. Subsequently the work became an integral. International Programme on Chemical Safety (IPCS), a. UNEP, ILO and WHO. In this manner, with the. The EHC. monographs have become widely established, used and recognized. As such. they include and review studies that are of direct relevance for the. However, they do not describe every study carried out. Both published and unpublished reports are. Preference is always given to. Unpublished data are only used when relevant published. A. detailed policy statement is available that describes the procedures. WHO (1. 99. 0) Revised Guidelines for the Preparation of Environmental. Health Criteria Monographs. PCS/9. 0. 6. 9, Geneva, World Health. Organization). Animal and. It is mandatory that research on. Helsinki Declaration. They represent a thorough evaluation of. These latter are the exclusive purview of national. Such meetings have been held in: Ispra, Italy. Oxford, United Kingdom, 1. Berlin, Germany, 1. North. Carolina, USA, 1. The selection of chemicals has been based on the. A designated staff member of. IPCS, responsible for the scientific quality of the document, serves. Responsible Officer (RO). The IPCS Editor is responsible for layout. The first draft, prepared by consultants or, more. IPCS Participating Institution, is based. International Register of. Potentially Toxic Chemicals, and reference data bases such as Medline. Toxline. Once the RO finds the document acceptable as. EHC contact points throughout the world who are asked to comment. The contact points, usually designated by. Participating Institutions, IPCS Focal Points, or. Generally. some four months are allowed before the comments are considered by the. RO and author(s). A second draft incorporating comments received and. Director, IPCS, is then distributed to Task Group. Their. function is to evaluate the accuracy, significance and relevance of. A summary and. recommendations for further research and improved safety aspects are. The composition of the Task Group is dictated by the. While observers. may provide a valuable contribution to the process, they can only. Chairperson. Observers do not. Task Group members. When the Task Group. They are required to sign a conflict of. Such a procedure ensures the transparency and. After approval by the Director. IPCS, the monograph is submitted to the WHO Office of Publications for. At this time a copy of the final draft is sent to the. Chairperson and Rapporteur of the Task Group to check for any errors. A comprehensive file of all comments. EHC monograph is maintained and is. The Chairpersons of Task Groups are briefed. Araki, Department of Public Health, Faculty of Medicine. University of Tokyo, Japan. Dr P. Baghurst, Division of Human Nutrition, Commonwealth Scientific. Industrial Research Organization, Adelaide, Australia. Dr D. Bellinger, Neuroepidemiology Unit, Gardner House, Children's. Hospital, Boston, Massachusetts, USA. Dr I. Calder, Occupational and Environmental Health, South Australian. Health Commission, Adelaide, South Australia, Australia. Dr D. A. Cory- Slechta, Department of Environmental Medicine. University of Rochester School of Medicine and Dentistry. Rochester, New York, USA. Dr K. Dietrich, Department of Environmental Health, Division of. Biostatistics and Epidemiology, University of Cincinnati College. Natural Products Expo West 2. Exhibitor List. You can use this page to view a list of all current 2. Expo West exhibitors and narrow down that list using a variety of search terms. Use of this information for any other purpose, including without limitation, solicitation purposes of any kind, is strictly prohibited. By accessing such information, you are agreeing to the aforementioned restrictions; if you do not agree to such restrictions, you may not use or access the exhibitor information for any purpose. To access the Expo Plan and have it sync with the Official Show App, click the Build My Schedule button below. You will need your Badge # and zipcode to access this feature. Square Root of Minus Garfield: Archive. About » Archive » Submit » Authors » Search » Random » Specials » Statistics » Forum » Facebook » RSS Feed Updates Daily. No. 1 Garfield in Haiku. No. 2 Garfield Plus Garfield. No. 3 Recursive Garfield. No. 4 Choose Your Own Garfield. No. 5 Qwantzfield. No. 6 Silent- Era Garfield. No. 7 Mystical Garfield. No. 8 Mix- n- Match Recaption Garfield. No. 9 Colour- Averaged Garfield: 2. No. 1. 0 Garfield Plus Penultimate Beat Panel. No. 1. 1 Garfield on a Neutron Star. No. 1. 2 The Garfield & Poochie Show. No. 1. 3 Garfocal. No. 1. 4 Ellen. 20. No. 1. 5 Garfield Divided by Garfield. No. 1. 6 Uncomfortably Close Garfield. No. 1. 7 The Garfield Code. No. 1. 8 Garfield/Jon Reversal. No. 1. 9 Garfield Divided by Garfield. No. 2. 0 Colour- Averaged Garfield: 1. No. 2. 1 NESfield. No. 2. 2 Garfield- Star Runner. No. 2. 3 Garfield Zen. No. 2. 4 Garfield meets mezzacotta. No. 2. 5 Reversed Garfield. No. 2. 6 Polar Coordinate Transform Garfield. No. 2. 7 Garfield Meets Zeus. No. 2. 8 Garfield Without Words. No. 2. 9 Circumference of Garfield. No. 3. 0 Garfield in Microgravity. No. 3. 1 Garfield in Wonderland. No. 3. 2 Garfield Without Words. No. 3. 3 Garfield's D- Leif Rag. No. 3. 4 Steganographic Garfield. No. 3. 5 Garfield #1 Gold Foil Embossed Collector's Edition. No. 3. 6 Garfield: The Video Game. No. 3. 7 Gadjifantolim. No. 3. 8 Garfield Rescue! No. 3. 9 Garfield on a Postcard. No. 4. 0 Recursive Thinking Garfield. No. 4. 1 Irregularfield. No. 4. 3 Fourier Transformed Garfield. No. 4. 4 Garfield Retold. No. 4. 5 Plush Garfield. No. 4. 6 Garfield's Inferno. No. 4. 7 Layered Garfield. No. 4. 8 Garfield Minus Jon. No. 4. 9 Andy Warfield. No. 5. 0 Reversed Garfield. No. 5. 1 Dark Side of the Lasagne. No. 5. 2 Plush Garfield. No. 5. 3 Garfield Minus Jon. No. 5. 4 Censored Garfield. No. 5. 5 Zoomed- out Garfield. No. 5. 6 Derivative of Garfield. No. 5. 7 No Time for the Dog! No. 5. 8 8. 67- 5. Jonny. 20. 09- 0. No. 5. 9 CAD + Garfield. No. 6. 0 Garfish. No. 6. 1 Garfield at Night. No. 6. 2 Flea Grid. No. 6. 3 John, Paul, George, and Ringo (and Garfield and Odie)2. No. 6. 5 xkcfield. No. 6. 6 Broken Vertical Hold Garfield. No. 6. 7 Signal to Noise. No. 6. 8 Welsh Sound Effect Garfield. No. 6. 9 Garfield Minus Garfield, Value Added: Help Me Do Nothing. No. 7. 0 Reversed Garfield - Variant. No. 7. 1 Garfield Minus Garfield, Value Added: Woo, woo, woo. No. 7. 2 Meditations on Garfield. No. 7. 3 Garfield Minus Garfield, Value Added: Mysterious. No. 7. 4 Plush Garfield: Reproportioned Jon. No. 7. 5 Liz Minus (Garfield and Jon)2. No. 7. 6 Identity Function Garfield. No. 7. 7 Garfield Minus Garfield Minus Jon. No. 7. 8 Garfield & Hobbes. No. 7. 9 Liz and Jon's Father Minus Jon but Plus Each Other. No. 8. 0 Zero Function Garfield. No. Garfield. 20. No. 8. 2 xkcd minus Garfield. No. 8. 3 Garfield minus xkcd. No. 8. 4 Garfield minus Jon plus Calvin. No. 8. 5 Paintfield. No. 8. 6 Garfield's Other Dog. No. 8. 7 Square Root of ((Minus Garfield) Squared)2. No. 8. 8 Mezzacotta Garfield. No. 8. 9 Garfield Minus More Garfield Than Ever. No. 9. 1 Imaginary Garfield: Mousey. No. 9. 2 The Guy Who Can't Draw Garfield. No. 9. 3 Garfield Top Twenty. No. 9. 4 Garfield Minus Everybody Else. No. 9. 5 Imaginary Garfield: Mouser. No. 9. 6 Garfield Minus Everything Else. No. 9. 7 Imaginary Garfield: Coffee Party. No. 9. 8 Exquisite Garfield. No. 9. 9 Pimp My Garfield. No. 1. 00 Recursive Garfield Redux. No. 1. 01 Garfield Retold Retold. No. 1. 02 Pulp Media Garfield. No. 1. 03 Garfield Divided by Cloverfield. No. 1. 04 Garfield Minus Characters. No. 1. 05 Politigarfield. No. 1. 06 Jon. 20. No. 1. 07 Birthday Garfield. No. 1. 08 Goldfield. No. 1. 09 April of No Sundays Collection. No. 1. 10 Garfield IN SPACE! No. 1. 11 Why So Serious? No. 1. 12 Barfield. No. 1. 13 Sunday Every Day. No. 1. 15 Trichromatic Garfield. No. 1. 16 Spacious Garfield. No. 1. 18 Cold- Warm Involution Garfield. No. 1. 19 Frozen Garfield. No. 1. 20 Dissociated Garfield. No. 1. 21 A Softer Cat. No. 1. 22 Lolfield. No. 1. 23 Cyclops Garfield. No. 1. 24 Krazy minus Kat. No. 1. 25 Mix and Match Garfield. No. 1. 26 Garfield Plus i times Odie. No. 1. 27 A Week in a Day. No. 1. 28 Garfield Minus (Garfield Minus Garfield)2. No. 1. 29 Frank Miller's Garfield. No. 1. 30 Square Roots of Garfield. No. 1. 31 Garfield: Lost in Translation Minus Garfield. No. 1. 32 Jon Loses His Lunch. No. 1. 33 Garklife. No. 1. 34 9 Garfield Lane. No. 1. 35 The Happiest Dog in the World. No. 1. 36 Jon's Boo- Boo. No. 1. 37 Sixth Roots of Garfield. No. 1. 38 Realfield. No. A Snail. 2. 00. No. 1. 40 Garfield Plus Tree. No. 1. 41 Garfield Recoloured. No. 1. 42 Bob and George featuring Odie. No. 1. 43 A Little Something Different. No. 1. 45 Garfield Negative Space. No. 1. 46 Mezzafield. No. 1. 47 Garfield's Contractual Requirement. No. 1. 48 An Unguarded Hamburger. No. 1. 49 House of Garfields. No. 1. 50 Is that just cool or what? No. 1. 51 Talking Garfield. No. 1. 52 Garfield Minus Garfield Minus Jon Minus Odie Minus Nermal Minus Arlene Minus Lyman Minus Liz Minus Pookie. No. 1. 53 Garfield Is the Perfect Disguise. No. 1. 54 Garf- life. No. 1. 55 It's Just One of Those Days. No. 1. 56 Square Root of Negative Garfield. No. 1. 57 Garfield Meets Unauthorised Calvin. No. 1. 58 Minus Garfield. No. 1. 59 urururururururur. No. 1. 60 (Garfield minus Jon) Divided by Garfield. No. 1. 61 Concerned Garfield. No. 1. 62 Garfield Retold Minus Garfield. No. 1. 63 Meta- Garfield. No. 1. 64 Jon's Chat Screen. No. 1. 65 Polterfield. No. 1. 66 Fun With Hair Day. No. 1. 68 Indexed Colour Garfield. No. 1. 69 The Bunny Slipper Diet. No. 1. 70 Ledge. No. 1. 71 Choose Your Own Punchline. No. 1. 72 Jon: Jon Minus Minus Mouse Catching. No. 1. 73 Comic Without Garfield. No. 1. 74 Jon: Jon's Snapped Mind. No. 1. 75 Garfield Really Minus Garfield. No. 1. 76 Garfield with Bad Words. No. 1. 77 Reversed Garfield, and ditto Jon. No. 1. 78 Darkfield. No. 1. 79 Garfield Minas Garfield. No. 1. 80 Garfield Cross Section A2. No. 1. 81 Jon Roughs It. No. 1. 82 Boomtown Cats. No. 1. 83 Little Garfield Lost. No. 1. 84 Garfield Cross Section B2. No. 1. 85 Humans Are Nice. No. 1. 86 Garfield Cross Section C2. No. 1. 87 Pokemon Orange. No. 1. 88 Impressionist Garfield. No. A Vagrant Minus Garfield! No. 1. 90 Garfield of the Old Republic. No. 1. 91 Garfield Miners Garfield. No. 1. 92 Garfield Mosaic. No. 1. 93 The Angriest Cat in the World. No. 1. 94 New Perspective. No. 1. 95 Jonfield. No. 1. 96 Beware of Giygas. No. 1. 97 Jon: Nap Attack. No. 1. 98 Variations on a Haircut #1. No. 1. 99 Garfield Replacement. No. 2. 00 Gar Field. No. 2. 01 thegarfieldian. No. 2. 02 Gravfield. No. 2. 03 Shadow Garfield. No. 2. 04 The Cat. No. 2. 05 Variations on a Haircut #2. No. 2. 06 Jon: Nap Attack for Salt. No. 2. 07 Reversed Text Garfield. No. 2. 08 Garfield Mosaic 2. No. 2. 09 Odiefield. No. 2. 10 Garfieldarama. No. 2. 11 Antiderivative of Square Root of Minus Garfield. No. 2. 12 (Re)create with Garfield! No. 2. 13 All- Star Garfield and Odie The Wonder Dog. No. 2. 14 Garfield at 5. No. 2. 15 Garfield + 2. Years. 20. 09- 1. No. 2. 17 Talking Scale Minus Garfield.. Garfield Music. 20. No. 2. 19 Gracefield. No. 2. 20 Mirror- Image Garfield. No. 2. 21 Replaced. No. 2. 22 Blue Screen of Garfield. No. 2. 23 Mirrored Garfield. No. 2. 24 Garfield as a Number. No. 2. 25 Jon - Why Jon Can't Go Grocery Shopping. No. 2. 26 Fluffy. No. 2. 27 Less Humour, More Story! No. 2. 28 Nagging Feeling. No. 2. 29 Fridge Logic. No. 2. 30 Just Look At That Gorgeous Garfield. No. 2. 31 Garfield Minas Tirith. No. 2. 32 Garfield Minus Garfield Minus Outside Panel Frames. No. 2. 33 Garfield/3. No. 2. 34 The Vampire Garfield Chronicles. No. 2. 35 Moooo. No. 2. 36 Garfield Cross Section D2. No. 2. 37 The Computer is Your Friend. No. 2. 38 Continuity: Positive. No. 2. 39 Unprovoked. No. 2. 40 Jon - The Prisoner. No. 2. 41 Continuity: Negative. No. 2. 42 Advantages to Growing Older. No. 2. 43 A Nightmare on Elm Street. No. 2. 44 Jon the Clueless Witness. No. 2. 45 Candid Camera Garfield. No. 2. 46 Head to Tail. No. 2. 47 Oh Snap! No. 2. 48 Catchless Garfield. No. 2. 49 garfield minus. No. 2. 50 Garfapteryx. No. 2. 51 Beware. No. 2. 52 Grey. 20. No. 2. 53 Garfloraled, Part 1. No. 2. 54 Almost Everywhere Zero Garfield. No. 2. 55 Fun With Hair Day Minus Garfield. No. 2. 56 It's an Old, Old World. No. 2. 57 Rice. 20. No. 2. 58 Garfloraled, Part 2. No. 2. 59 Garfield Shrink & Re- enlarge, Part 1. No. 2. 61 Garfield Shrink & Re- enlarge, Part 2. No. 2. 62 Jon, Paranoid. No. 2. 63 Garfield Shrink & Re- enlarge, Part 3. No. 2. 64 JPEGarfield. No. 2. 65 Garfield Shrink & Re- enlarge, Part 4. No. 2. 66 Mirror Universe Garfield. No. 2. 67 Garfloraled, Part 3. No. 2. 68 Garfield Linus Garfield. No. 2. 69 Morbid Garfield. No. 2. 70 RPGarfield. No. 2. 71 Elvield. No. 2. 72 Grinfield. No. 2. 73 Night Garfield. No. 2. 75 One Small Push.. No. 2. 76 Small Talk. No. 2. 77 Many- Worlds Garfield. No. 2. 78 Garfield Dream. No. 2. 79 Vertical Garfield. No. 2. 80 Yoda Garfield. No. 2. 81 Breaking the 4th Wall. No. 2. 82 Anaglyphfield. No. 2. 83 Free Floating Garfield. No. 2. 84 Cats of the Old Republic. No. 2. 85 Gallagherfield. No. 2. 86 Lemmy Arbuckle Minus Garfield. No. 2. 87 Delta Garfield. No. 2. 88 Garbert, Evil Director of Human Resources. No. 2. 89 Jon Snapped. No. 2. 90 Create. Garfield. 20. 10- 0. No. 2. 91 Pictures for Sad Kittens. No. 2. 92 Clobberin' Time. No. 2. 94 Tung. 20. No. 2. 95 Feet. 20. No. 2. 96 Nermal Minus Garfield. No. 2. 97 Garfield versus Odie's Dark Abyss of a Soul. No. 2. 98 A Bomb. No. 2. 99 2 Panel Garfield. No. 3. 00 Garfield Minus Garfield Minus Speech Bubbles. No. 3. 02 Looky Looky. No. Wolverine. 20. No. 3. 05 Hey Evelyn, Nice Shot. No. 3. 06 Garfield Minus Food. No. 3. 07 Subliminal Garfield. No. 3. 08 Window Blind Story. No. 3. 09 Calm Break. No. 3. 10 Garfield, 2 Seconds Out- of- Sync. Oxford University Press is a department of the University of Oxford. It furthers the University's objective of excellence in research, scholarship, and education by publishing worldwide.
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